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$ sustaining, monthly one-time contribution
In the past 20 years, insulin prices have risen nearly ninefold. As a result, one in four diabetics in the U.S. have reported rationing insulin. At Open Insulin we work to ensure that communities in need have access to safe, affordable, high-quality insulin. To aid that, we are developing a small-scale model for decentralized manufacturing of biopharmaceuticals run by and for local communities. We aim to accomplish this by making the technology and knowledge for the purification of insulin available to community groups, and then organizing those groups to produce insulin.
Making Open Insulin available to consumers is estimated to take several years after proceeding through various stages:
In addition, we are developing and vetting open-hardware equivalents to production equipment to further reduce production costs.
We have been able to successfully strategize and demonstrate the feasibility of this project, with the help of passionate volunteers and part-time workers. We have data strongly suggesting that we can produce both long-acting (glargine) and rapid-acting (lispro) insulin analogs.
Our monthly lab expenses are paid off by individual donations ~ $800/month. We launched fundraising campaigns to buy equipment (January 2020, $6,500 for a bioreactor). We have a grant with the Open Science Foundation to pay for a part-time worker.
Your donation will help us get closer to our goal. With a strong financial situation, we can pay for lab supplies, acquire lab equipment, recruit scientists, and pay for consultation fees for regulation and manufacturing experts.
We will widely share our knowledge about microorganism engineering, protein production, navigating regulatory processes, and best practices for biomedicine production via informal publications, technical documentation, and discussion with other organizations with similar missions.
Until: 12/31/2022 12:00am
Speaking as a Nurse and Mother, I hope that together we can improve access to lifesaving medicine for the sake of our Children's health and future. Insulin prices in the United States have shot up exponentially in the last 30 years, reaching sums of $275 per vial. With rising cases of diabetes, these numbers are far from sustainable. Open Insulin is developing the first freely available, open organisms for insulin production that will be practical for small-scale, locally-based groups to use. With your help, the Open Insulin project can get back into the lab to continue this incredible work, fighting for affordable insulin one step at a time.0 supporters $0 raised
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